Birc2 CLIA Kit for Mouse(Mus musculus) | EIAab.comBirc2 CLIA Kit for Mouse(Mus musculus)

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Birc2 (Gene name),

Baculoviral IAP repeat-containing protein 2 (Protein name ), BIRC2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Birc2(Birc3;Iap2);

Protein name:

Baculoviral IAP repeat-containing protein 2;

Alternative:

Inhibitor of apoptosis protein 2(IAP-2;mIAP-2;mIAP2);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with DIABLO/SMAC and with PRSS25; these interactions inhibit apoptotic suppressor activity. Interacts with CASP9.

Function:

Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2).

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

612

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

612:

GTIKGTVRTF | LS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q62210

KEGG:

mmu:11797

Pfam:

PF00653

String:

Q62210

UniGene:

Mm.335659

Uniprot:

Q62210

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ELISA Kit for Mouse Baculoviral IAP repeat-containing protein 2

Cat.:

E10854h

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96T

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ELISA Kit for Mouse Baculoviral IAP repeat-containing protein 2

Cat.:

E10854m

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Manual:

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96T

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CLIA Kit for Mouse Baculoviral IAP repeat-containing protein 2

Cat.:

U10854m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Baculoviral IAP repeat-containing protein 2

Cat.:

U10854h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Baculoviral IAP repeat-containing protein 2

Cat.:

P10854Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Baculoviral IAP repeat-containing protein 2

Protein for Mouse Baculoviral IAP repeat-containing protein 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤5.9%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤8.4%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

Recovery was determined by spiking various levels of BIRC2 into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	95	91-101
Plasma	97	93-104

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of BIRC2 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	92-99%	90-102%	91-101%	88-103%
EDTA plasma(n=5)	90-105%	89-107%	92-101%	95-99%
heparin plasma(n=5)	93-100%	94-102%	91-103%	91-105%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins."
Rothe M. , Pan M.-G. , Henzel W.J. , Ayres T.M. , Goeddel D.V.
Cell83:1243-1252(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
2.

"Genomic characterization of the mouse inhibitor of apoptosis protein 1 and 2 genes."
Liston P. , Lefebvre C. , Fong W.G. , Xuan J.Y. , Korneluk R.G.
Genomics46:495-503(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Skeletal muscle.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
4.

"c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation."
Varfolomeev E. , Goncharov T. , Fedorova A.V. , Dynek J.N. , Zobel K. , Deshayes K. , Fairbrother W.J. , Vucic D.
J. Biol. Chem.283:24295-24299(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS AN E3 UBIQUITIN-PROTEIN LIGASE

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